CHONDROBLASTOMA CYTOLOGY PDF

The authors document the cytological features on fine-needle aspiration cytology of a chondroblastoma which appeared as a lytic lesion in the. Chondroblastoma is an uncommon benign cartilage producing neoplasm with a characteristic epiphyseal location. This report documents the. Chondroblastoma is a rare primary bone tumor of young people .. Fine needle aspiration cytology of chondroblastoma of bone. Cancer.

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Magnetic resonance imaging of leg showed abnormal marrow infiltration in medullary cavity of head and upper shaft of fibula hypo-intense on T1-weighted T2-weighted sequences and hypo-to hyper-intense on short tau inversion recovery STIR cjondroblastoma, the vertical length being 8 cm approximately.

Chondromyxoid fibroma closely mimics chondroblastoma due to the presence of myxoid background substance, chondroid fragments and osteoclastic giant cells; however, its spindle-shaped or stellate, fibroblast-like tumour cells in contrast to the mononuclear cells cjondroblastoma chondroblastoma with distinct cell borders, round-to-oval nuclei and dense eosinophilic cytoplasm help in differentiating these two entities.

Pathology Outlines – Chondroblastoma

Accepted May 3. The FNAC smears, stained with giemsa stain, showed neoplastic mononucleated and binucleated chondroblasts, multinucleated osteoclast-like giant cells, and chondromyxoid matrix fragments representing early cartilage in hemorrhagic background.

Fine needle aspiration cytology of chondroblastoma chondroblastona bone. All the giant cell containing lesions fall under the differential diagnosis of chondroblastoma. Aggressive scapular chondroblastoma with secondary metastasis: Instead, stellate cells with pleomorphism are noted. No mitotic figures were seen.

Fine needle aspiration cytology of chondroblastoma of the fibula

Chondromyxoid fibroma of the mandible: The authors document the cytological features on fine-needle aspiration cytology FNAC of a chondroblastoma which appeared as a lytic lesion in the upper end of the right fibula, an uncommon site, in an year-old male patient. Back to cited text no.

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Neoplastic cells with ovoid to spindled nuclei. Clinical diagnosis was giant cell tumor of bone. None, Conflict of Interest: The cytologic features of the chondroblasts and chondroid matrix are the diagnostic hallmarks of chondroblastoma.

In both the cases, the smears chondroblaetoma abundant material that was predominantly composed of chondromyxoid matrix with cytolofy cellularity. High failure rate of aspiration cytology in bone tumors is mainly due to the hardness and fibrous nature of the tumors and if they are guarded by thick cortex leading to difficulty in piercing the needle.

Diagnosis of chondroblastoma was made on cytology. The overlying skin was unremarkable. Their anatomic and theoretical basis with an emphasis chondroblastima radiology, pathology and clinical biology. High failure rate of cytoogy cytology in bone tumors is mainly due to the hardness and fibrous nature of the tumors and if they are guarded by thick cortex leading to difficulty in piercing the needle.

Fine-needle aspiration cytology of chondromyxoid fibroma: The intramedullary cartilage tumors. Daneshbod Y, Khademi B.

Chondroblastoma of the skull and facial bones. Differentiation of chondroblastoma from solid ABC is a challenge as well. Am J Pathol ; NandedkarPrashant Yeshwanteand Preeti Rihal. One of the two cases had an unusual location in the temporomandibular region and the other was located in the epi-metaphyseal region of the yctology humerus.

Atlas of tumor pathology, second series, fascicle 5. We report here a unique case of chondroblastoma of the fibula with extracortical soft tissue invasion.

Author information Copyright and License information Disclaimer. Differential diagnosis on cytology is discussed. Diagnostic cytological features of condroblastoma are sheet-like clusters of mononuclear cells, scattered osteoclast-like giant cells and focal chondroid matrix formation. Financial support and sponsorship Nil.

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Armed Forces Institute of Pathology; A report of two cases. Correspondence to Dr Shagufta Qadri, moc.

The extra-osseous component was large and measured 7. Both the cases being presented had the typical clinical features of pain and swelling. Extracortical soft tissue invasion or metastasis is rarely seen. Various investigations like routine blood and urine examination, serum acid and alkaline cytoogy, serum calcium and phosphorus were within normal limits.

It usually affects the young with a peak incidence in the second and third decades of life and a slight male preponderance. At cytology, the presence of giant cells, chondroid matrix, mononuclear cells with nuclear indentation, and grooving along with glassy, vacuolated cytoplasm are characteristic of chondroblastoma. There was no recurrence observed on 2-year follow-up of the case.

Cytological diagnosis of chondroblastoma: diagnostic challenge for the cytopathologist

Case Report Case 1 A year-old male presented with pain and diffuse swelling on the knee joint since 2 months. They include the neoplastic mononuclear cells chondroblastsmultinucleate giant cells and chondroid matrix.

Chondromyxoid fibroma CMF is one such tumor that is characterized by incomplete cartilage differentiation. Fine needle aspiration cytology in the management of tumors and tumor like lesions of bone.

How to cite this URL: Thus CMF was confirmed yctology histopathology. Diagnostic pitfalls in fine-needle aspiration cytology of temporomandibular chondroblastoma: Cytologic features of primary chondroid tumors of bone in crush preparations.