Drug monographs for CEFPODOXIME PROXETIL provide an overview of the drug product, therapeutic uses, key development issues, regulatory information. Cefpodoxime Proxetil reference guide for safe and effective use from the For empiric outpatient treatment of CAP when risk factors for drug-resistant S. Cefpodoxime is indicated for the treatment of the following infections when caused by susceptible pathogens (see sections and ) in adults.
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This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. In cases of severe renal insufficiency it may be necessary to reduce the dosage regimen dependent on the creatinine clearance see section 4. Staphylococcus aureus methicillin resistant Aerobic Gram negative organisms Morganella morganii Pseudomonas aeruginosa. Pharmaceutical form Film-coated tablet Coral red, elliptical, film-coated tablets debossed with ‘C’ on one side and ’62’ on the other side.
Dizziness has been reported during treatment with cefpodoxime and may affect the ability to drive and use machines. To email a medicine you must sign up and log in. Neither party may assign this Agreement to any third party without the prior written consent of the other party. Not recommended by CDC as first-line treatment. In the event you refuse to agree to any such new agreement, the AAP will, if requested, refund any unearned portion of your subscription fee.
Upper respiratory monogralh infections: Advise patients that antibacterials including cefpodoxime should only be used to treat bacterial infections and not used to treat viral infections e.
Cephalosporin susceptibility among Neisseria gonorrhoeae isolates–United States, It is recommended that the INR should be monitored frequently during and shortly after co-administration of cefpodoxime with an oral anti-coagulant agent. Pfoduct AAP is a Section c 3not-for-profit corporation, and as such, does not participate in any political activities.
Enterobacteriaceae uncomplicated UTI only.
IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults. Bronchitis ciprofloxacinamoxicillindoxycyclineazithromycinAugmentinMore Children beyond neonatal period: If your institution provides your access to this website, you may link that access to your individual AAP account.
We comply with the HONcode standard for trustworthy health information – verify here. There are no or limited amount of data from the use of cefpodoxime in pregnant women.
Princeton, NJ; Sep. Ptoduct authorisation number s 9. This warranty gives you specific monograpn rights, and you may also have other rights which vary from state to state. This binding is non saturable in type. In consideration of payment of the applicable subscription fee, the AAP is willing to provide access to the Materials to you and, if applicable, your Users as defined belowsubject to all of the following terms. Cirrhosis does not affect the half-life or renal clearance of the drug.
Subscribe to receive email notifications whenever new articles are published. Multiple dose pharmacokinetics of cefpodoxime in young adult and elderly patients. Below this value, pharmacokinetic studies indicate an increase cefpodoximf plasma elimination half-life and the maximum plasma concentrations, and hence the dosage should be adjusted appropriately. Before beginning treatment, it should be established whether the patient has a history of severe hypersensitivity reactions to cefpodoxime, to other cephalosporins or to any other type of cfepodoxime agent.
Haematological disorders such as reduction in haemoglobin, thrombocytosis, thrombocytopenia, leucopenia and eosinophilia Very rare: Film-coated tablet Coral red, elliptical, film-coated tablets debossed with ‘C’ on one side and ’62’ on the other side.
Resistance to cephalosporins results from a variety of mechanisms: Importance of informing patients with phenylketonuria that cefpodoxime oral suspension may contain aspartame, depending on the manufacturer.
In case of severe hypersensitivity reactions, treatment with cefpodoxime must be discontinued immediately and adequate emergency measures must be initiated. For group enrollment, access to the Materials is limited to you and your authorized Users for whom you have obtained an authorized subscription. Treatment with anti-infectives alters normal colon flora and may permit overgrowth of Clostridium difficile.
Treatment of acute maxillary sinusitis caused by susceptible S. Adverse drug reactions are listed below by system organ class and frequency. Closely monitor renal function when used concomitantly with nephrotoxic drugs 1 Elk Grove Village, IL: Cephalosporins may be absorbed onto the surface monogrwph red cell membranes and react with antibodies directed against the drug.
Cefpodoxime Proxetil Monograph for Professionals –
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Cefpodoxime proxetil is a prodrug that is inactive until hydrolyzed in vivo to cefpodoxime. If any term of this Agreement is held to be invalid, the parties agree that such invalidity will not affect the remaining terms.
Infect Control Hosp Epidemiol. Due to the benefit of antibiotic treatment, the use of cefpodoxime may be considered during pregnancy if necessary.
In geriatric patients, plasma half-life averages 4. Five day treatment of pharyngotonsillitis with cefpodoxime proxetil. Reconstitute oral suspension at time of dispensing by adding amount of water specified on the container in 2 portions; invert bottle and shake after each addition.
Klein M, for the International Study Group. You may then access the website remotely and unlock features for individual accounts.